Location:Communal Instruments
Communal Instruments
Last updated at
2013-08-15

   The SPST maintains a large number of instruments for use on a walk-up basis. Our Instrumental Analysis Center is open to Tianjin University researchers from all schools and departments, as well as users from other Universities, Institutes or Industries.

   Some of these instruments require training before investigators are permitted to use them. See the listing below for details on individual instruments.

NMR Spectrometer

Model: AVANCE III 600 MHz Digital NMR Spectrometer
Manufacturer: Bruker Co., CH
Specification

 The AVANCE III 600M NMR spectroscopy is suited for the routine experiments, such as 1H、13C、1H-1H NOESY、1H-1H TOCSY、1H-13C HSQC、HMBC、15N-1H HSQC spectrometers and 3D spectrometers.
 Normal geometry 2H/1H/BB BBFO SmartProbe capable of tuning to nuclei of 109Ag-19F on the broadband channel. Autolock, autoshim, autotune capabilities. Variable temperature capabilities ranging from -150 °C to +150 °C.
 Inverse geometry 2H/1H/13C/BB inverse probe with a dedicated 13C channel and 109Ag - 19F range on the broadband channel. Autolock and autoshim capabilities. Variable temperature capabilities ranging from -150 °C to +150 °C.
 BCU-I Bruker chiller for VT experiments in the -30 °C to +150 °C range.
 Liquid N2 dewar with heat exchanger for VT experiments down to -150 °C.
 SampleExpress 16-sample changer.
Main Applications

 Structural investigations of bio-macromolecules,
 QNMR of agrochemicals
 Impurity profiling of pharmaceuticals
 Drug-DNA interactions and Rare organometallic species

 

Ultra Performance Liquid Chromatograph/ Quadrupole Time-of-flight Mass Spectrometer

Model: 1290 UPLC / micrOTOF-Q II
Manufacturer: Agilent Co., US/Bruker Co.,DE
Specification

 Ion source options: ESI; APCI
 Mass Range (m/z): 50- 40,000 m/z
 Resolution:17,500 (FWHM)  922 m/z
 Acquisition rate: (2GHz sampling rate) 20 Hz (profile and peak detected spectra to disk)
 Mass Measurement Accuracy: <3 ppm RMS Error (internal), 5 ppm RMS Error (external)
 Dynamic Range: 104 
 Temperature compensated
 Flow Range: 0.010- 5.000 ml/min
 Max Pressure: 15000 psi
Main Applications
:  qualitative and quantitative analysis
 Environmental analysis: the assessment of pesticide residue, contaminated sediments and water quality
 Bioscience & Metabonomics study: the study of biological samples and pharmaceutical product, such as organic acids, amines, amino acids, nucleotides and heterocyclics
 Chemical analysis: the research of materials and polymer related to organic synthesis
 Botanical products: the separation of multi-compounds in botanical products and Chinese traditional medicine

 

High Performance Liquid Chromatograph/ Ion Trap Mass Spectrometer

Model: 6310 Ion Trap MS /1200 HPLC with DAD
Manufacturer: Agilent Co., US
Specification:
 Ion source options: ESI
 Mass Range (m/z): 50- 2,200 m/z
 Resolution: < 0.35 to 4 FWHM (u) (depending on model, scan speed and m/z)
 Scanning rate: 800 to 27,000 u/s (Depending on model)
 Flow Range: 0.010- 5.000 ml/min
 Max Pressure: 400 bar
Main Applications:  qualitative and quantitative analysis
 The 1200 series Agilent Liquid Chromatograph (HPLC) is equipped with a binary pump system, thermostatted autosampler with multi-well plate capability, thermostatted column compartment with switching valve, a UV-VIS diode array detector (DAD), and analytical fraction collector, that can be operated in time- and peak-triggered mode.
 The Agilent 6310 ion trap mass spectrometer can be operated in-line with the LC system (LC/MS) or completely separate, e.g. for the analysis of purified fractions collected with the analytical fraction collector.
 The system is capable of performing MS(11) although unless very high amounts of sample can be ionized and trapped, MS(3) or MS(4) are probably more realistic limits for most applications.
 


Elemental Analyzer


 Model:Vario Micro cube (CHNS / CHN)
Manufacturer:Elementar Co., DE
Specification:
 High temperature combustion: quantitative sample digestion at up to 1200°C – with ten years furnace warranty (1800°C at the point of combustion when tin foil is used). This is the prerequisite for 100% recovery also with samples difficult to combust. Jet injection of oxygen directly to the sample leads to highest oxygen concentrations at the point of combustion and low gas consumption
 Largest weighing range: from micro (<1mg) to macro (800mg soil) sample weight, depending on requirenemtns up to 20mg organic matter
 Largest dynamic range of element concentrations and element ratio: up to 7 mg C abs. or 2 mg N abs. (or 100%), from ppm to 100%
 Temperature programmed Desorption (TPD): Separation of gaseous components with one TPD column for perfect separation without peak overlapp. Automated optimization of the time per analysis
Main Applications
 Analyzer for simultaneous C-, H-, N-, S- analysis: Innovative universal instrument for the determination of the element contents in organic and most inorganic solids and liquids (capsule sealing press as accessory).
 


FT-IR Spectroscopy

  Model:TENSOR 27
Manufacturer:Bruker Co.,DE
Specification:
 Source: mid-IR range form 4000 to 400 cm−1
 Beamsplitter: KBr
 Detector: mercury-cadium-telluride (MCT), liquid nitrogen-cooled (10 times more sensitive than room-temperature deuterated triglycine sulfate detectors)
 Pathway: dehumidifier and dry nitrogen gas purge
 Resolution: 1 cm−1
 Software instrument control + data processing: OPUS
 This single-beam instrument requires collection of background spectrum before sample spectrum.
Main Applications
 The FT-IR spectrometer TENSOR 27 (Bruker) is to be used for measurements in the mid-infrared wavelength range. It is suitable for qualitative and quantitative spectra interpretations as well as for structure elucidation.
FT-IR spectrometer that can rapidly identify, quantify and verify your routine samples, TENSOR is the right tool for your laboratory. It combines the highest performance and outstanding flexibility with an intuitive and easy to operate interface. 

 

Polarimeter

 

Model:Autopol II
Manufacturer:Rudolph Co., US
Specification:
 Accuracy 0.002°C,  0.2% above 1°
 589nm and 546nm wavelengths. (A total of 2-4 wavelengths may be ordered initially or as needed)
 Built in thermoprobe for temperature measurement.
 Temperature Probe is covered with a micron thick glass coating to stand up to high molar Hydrochloric Acids used by some pharmaceutical labs.
 Windows Embedded 7 for direct connection to the network server and flexible USB Printing.
Main Applications
 Quality and process control applications, both in the laboratory or on-line in the factory, are found throughout the pharmaceutical, essential oil, flavor, food and chemical industries.
 Evaluating and characterizing optically active compounds by measuring their specific rotation and comparing this value with the theoretical values found in literature.
 Investigating kinetic reactions by measuring optical rotation as a function of time.
 Monitoring changes in concentration of an optically active component in a reaction mixture, as in enzymatic cleavage.
 Analyzing molecular structure by plotting optical rotatory dispersion curves over a wide range of wavelengths.
 Distinguishing between optical isomers.

 

Mini Spray Dryer

Model:B-290/B-295
Manufacturer:Buchi Co., CH
Specification:
 Evaporative Capacity - 1.0/hr H2O, higher for organic solvents
 Air Flow - Max of 35 cu. M/hr
 Max. Temperature Input - 220° C
 Heating Capacity - 2300 W
 Heating Control - PT-100, Fuzzy Logic, Control Accuracy +/- 3° C
 Spray Gas - Compressed air or nitrogen, 200 - 1000 l/h, 5-8 bar
 Nozzle Diameter - 0.7 mm Standard, 1.4 and 2.0 mm as accessories
 Nozzle Cap - 1.4 mm and 1.5 mm diameter
 Mean Dwell Time - 1.0 - 1.5 seconds
 Possible particle diameter range - 1-25 um
 Materials in contact with product - Acid-resistant stainless steel, 3.3 Borosilicate glass, FPM Silicone
Main Applications
 various fields where the production of a free powder sample is required. B-290 has successfully processed samples in the following areas: Beverage, Flavours and colourings, Milk and egg products, Plant and vegetable extracts, Pharmaceuticals, Synthetics Heat sensitive materials, Plastics polymers and resins, Perfumes, Blood, Ceramics and superconductors Biochemicals, Dyestuffs, Soaps and detergents, Foodstuffs, Adehesives, Oxides, Textiles, Bones, Teeth and tooth amalgam and many others.
 


Laboratory Fluid Bed Processor


Model:Minilab
Manufacturer:Diosna Co., DE
Specification:
 MINI-LAB for quick product and process development on a  small scale
 Multi-purpose units for the laboratory
 MIDI-LAB for higher performance and bigger product batches
 3 exchange bowls 7l / 10l / 13l
 glass or stainless steel bowls
 Top- or Bottom-Spray-processes
 plug and play: simple to operate, easy to clean
Main Applications
 DIOSNA fluid bed plants are used successfully worldwide. The laboratory plants MIDI-LAB were developed especially for R&D purposes. Drying, spray or melt granulation, spray cooling, powder coating, pellet coating, Wurster processing or instantising: a wide range of applications can be realised on laboratory scale.